Projects
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Projects
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The Pakistan Risk of Myocardial Infarction Study (PROMIS)

The burden of coronary heart disease (CHD) is increasing at a greater rate in South Asia than in any other region globally, but there is little direct evidence about its determinants. The Pakistan Risk of Myocardial Infarction Study (PROMIS) (PI: Danish Saleheen) is an epidemiological resource to enable reliable study of genetic, lifestyle and other determinants of CHD in South Asia.

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Risk Assessment of Cerebrovascular Events study (RACE)

Stroke is the leading cause of sustained neurological disability worldwide and, after coronary heart disease and cancer, the third leading cause of death globally.The burden of this condition is rising, especially in low- and middle-income countries, where there is typically limited capacity to deal with the personal, social and economic impact of these increases.

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Pakistan Type-2 Diabetes Study

Type 2 Diabetes (T2D) is a growing epidemic in South Asians with a higher prevalence as compared to other ethnicities around the world. Pakistan was ranked amongst the top 10 countries of the world with highest number of people with diabetes in 2004 and an estimated 14.5 million Pakistanis will have diabetes by the year 2025. According to a recent national survey, 35% people over the age of 45 years have diabetes in Pakistan. Similar observations of higher prevalence of T2D amongst immigrant South Asians have also been made.

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1000 Genomes Project – Pakistan

The 1000 Genomes Project is the first large scale project that aims to sequence the genomes of 2500 people of different global ethnicities, to provide a comprehensive resource on human genetic variation. The goal of the 1000 Genomes Project is to find most genetic variants that have frequencies of at least 1% in the populations studied. Such information will be useful for a range of genetic investigations specifically including genome-wide association studies.

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